Kirstie Alley and her weight have been the subject of many of Conan O’Brien’s jokes and lets just say she’s fed up with it. Kirstie took to her Twitter page and blasted the talk show host and also got Star Jones in on the assault. Alley’s angry tweets, which refer to O’Brien as “she” and makes a crude comment about his privates, were sent to a celebrity pal who knows what it’s like to be ridiculed for a weight problem – Star Jones.

“ONE B—- I’m gonna knck [sic] out next time I see her is CONAN O’B—- O’BRIAN [sic],” Alley fumed. “That guy acts like I bit his d— off.”

Jones responded back, “You know Conan probably ‘wanted some’ and you chumped him … I know a few brothers from Brooklyn who owe me! LOL Like I don’t know what it is to be called FAT, UGLY & LAZY. Hell, people called me that on TV & in print!”

Conan O’Brien wasn’t scared, this is how he responded on his show: